Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 221,894,035 papers from all fields of science
Search
Sign In
Create Free Account
torsemide
Known as:
1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea
, Torasemidum
, 1-isopropyl-3-((4-(3-methylphenylamino)pyridine)-3-sulfonyl)urea
Expand
An anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
23 relations
Broader (4)
Antihypertensive Agents
Diuretics
Sodium Potassium Chloride Symporter Inhibitors
Sulfonamides
Anuria
CYP2C8 protein, human
CYP2C9 protein, human
Congestive heart failure
Expand
Narrower (1)
Luprac
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Multi-residue analysis of pharmaceutical compounds in wastewaters by dual solid-phase microextraction coupled to liquid chromatography electrospray ionization ion trap mass spectrometry.
N. Unceta
,
M. C. Sampedro
,
Nor Kartini Abu Bakar
,
A. Gómez-Caballero
,
M. Goicolea
,
R. J. Barrio
Journal of Chromatography A
2010
Corpus ID: 1673001
2009
2009
Linking binge alcohol-induced neurodamage to brain edema and potential aquaporin-4 upregulation: evidence in rat organotypic brain slice cultures and in vivo.
Kumar Sripathirathan
,
JamesM . Brown
,
E. Neafsey
,
M. Collins
Journal of Neurotrauma
2009
Corpus ID: 37464469
Brain edema and derived oxidative stress potentially are critical events in the hippocampal-entorhinal cortical (HEC…
Expand
Highly Cited
2005
Highly Cited
2005
Electrochemical characterisation of the human cytochrome P450 CYP2C9.
D. Johnson
,
B. Lewis
,
D. Elliot
,
J. Miners
,
L. Martin
Biochemical Pharmacology
2005
Corpus ID: 46458002
Highly Cited
1997
Highly Cited
1997
Different contributions of cytochrome P450 2C19 and 3A4 in the oxidation of omeprazole by human liver microsomes: effects of contents of these two forms in individual human samples.
H. Yamazaki
,
K. Inoue
,
Shaw Pm
,
Checovich Wj
,
F. Guengerich
,
Tsutomu Shimada
Journal of Pharmacology and Experimental…
1997
Corpus ID: 7993326
Omeprazole 5-hydroxylation and sulfoxidation activities were determined in liver microsomes of different humans whose levels of…
Expand
Highly Cited
1997
Highly Cited
1997
Allelic and functional variability of cytochrome P4502C9.
C. Bhasker
,
J. Miners
,
S. Coulter
,
D. Birkett
Pharmacogenetics (London)
1997
Corpus ID: 41241253
Single nucleotide substitutions are known to result in a different amino acid at one of four sites in cytochrome P4502C9 (CYP2C9…
Expand
Highly Cited
1995
Highly Cited
1995
Human hepatic cytochrome P450 2C9 catalyzes the rate-limiting pathway of torsemide metabolism.
J. Miners
,
D. Rees
,
L. Valente
,
M. E. Veronese
,
D. Birkett
Journal of Pharmacology and Experimental…
1995
Corpus ID: 23425297
Tolyl methylhydroxylation is the rate-limiting step in the elimination of torsemide, a newly developed diuretic, in humans in…
Expand
Review
1994
Review
1994
Pharmacological classification and renal actions of diuretics.
Jules B. Puschett
The Cardiology
1994
Corpus ID: 23236211
Diuretics may be classified according to their chemical structure, their mechanism and site of action within the nephron, and…
Expand
1992
1992
Effect of inhaled furosemide and torasemide on bronchial response to ultrasonically nebulized distilled water in asthmatic subjects.
A. Foresi
,
A. Pelucchi
,
B. Mastropasqua
,
G. Cavigioli
,
R. Carlesi
,
L. Marazzini
American Review of Respiratory Disease
1992
Corpus ID: 25524725
Inhaled furosemide has been shown to reduce the bronchoconstriction induced by several indirect stimuli, including ultrasonically…
Expand
Highly Cited
1988
Highly Cited
1988
Pharmacokinetics and metabolism of torasemide in man.
G. Neugebauer
,
E. Besenfelder
,
E. von Möllendorff
Arzneimittel-Forschung
1988
Corpus ID: 10077688
Torasemide (1-isopropyl-3-([4-(3-methyl-phenylamino)pyridine]-3- sulfonyl)urea) is a potent new loop diuretic. The…
Expand
1988
1988
Comparison of the pharmacokinetics and pharmacodynamics of torasemide and furosemide in healthy volunteers.
M. Lesne
Arzneimittel-Forschung
1988
Corpus ID: 41071846
The pharmacodynamic effects and the pharmacokinetic parameters of torasemide (1-isopropyl-3- ([4-(3-methyl-phenylamino)pyridine…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE