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tetrahydrodeoxycorticosterone
Known as:
3 alpha,5 beta-tetrahydrodeoxycorticosterone
, THDOC
, 3,21-dihydroxypregnan-20-one
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National Institutes of Health
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Related topics
Related topics
10 relations
Broader (4)
Anesthetics
Anti-Anxiety Agents
Neurohormones
desoxycorticosterone
Hypothalamic Hormones
Neurosecretory Systems
analogs & derivatives
Narrower (3)
Melatonin
allotetrahydrodeoxycorticosterone
tetrahydrodeoxycorticosterone, (3beta,5alpha)-isomer
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Etomidate, propofol and the neurosteroid THDOC increase the GABA efficacy of recombinant α4β3δ and α4β3 GABAA receptors expressed in HEK cells
P. Meera
,
R. Olsen
,
T. Otis
,
M. Wallner
Neuropharmacology
2009
Corpus ID: 20002634
Review
2008
Review
2008
The neurosteroid system: Implication in the pathophysiology of hepatic encephalopathy
S. Ahboucha
,
R. Butterworth
Neurochemistry International
2008
Corpus ID: 24327670
Review
2007
Review
2007
Social isolation stress and neuroactive steroids
M. Serra
,
E. Sanna
,
M. Mostallino
,
G. Biggio
European Neuropsychopharmacology
2007
Corpus ID: 25098885
Review
2003
Review
2003
Is there a physiological role for the neurosteroid THDOC in stress-sensitive conditions?
D. Reddy
TIPS - Trends in Pharmacological Sciences
2003
Corpus ID: 44829415
Highly Cited
1998
Highly Cited
1998
Stress and neurosteroids in adult and aged rats
M. Barbaccia
,
A. Concas
,
M. Serra
,
G. Biggio
Experimental Gerontology
1998
Corpus ID: 25216297
Highly Cited
1997
Highly Cited
1997
Neurosteroid Prolongs GABAA Channel Deactivation by Altering Kinetics of Desensitized States
W. Zhu
,
S. Vicini
Journal of Neuroscience
1997
Corpus ID: 18020683
Fast applications of GABA (1 mm) to nucleated and outside-out patches excised from granule neurons in cerebellar slices from…
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Highly Cited
1997
Highly Cited
1997
Influence of gender and brain region on neurosteroid modulation of GABA responses in rats.
Marlene A. Wilson
,
R. Biscardi
Life Science
1997
Corpus ID: 19311697
Highly Cited
1996
Highly Cited
1996
GABAA‐receptor‐mediated effects of progesterone, its ring‐A‐ reduced metabolites and synthetic neuroactive steroids on neurogenic oedema in the rat meninges
V. Limmroth
,
Won-Suk Lee
,
M. Moskowitz
British Journal of Pharmacology
1996
Corpus ID: 9429078
1 The effects of progesterone, its A‐ring‐reduced metabolites, allopregnanolone, tetrahydroxydeoxycorticosterone and the…
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Highly Cited
1992
Highly Cited
1992
Effects of steroids on gamma-aminobutyric acid receptors expressed in Xenopus oocytes by poly(A)+ RNA from mammalian brain and retina.
R. Woodward
,
L. Polenzani
,
R. Miledi
Molecular Pharmacology
1992
Corpus ID: 22541893
Electrical recordings were made in Xenopus oocytes to study the modulatory effects of steroids on gamma-aminobutyric acid (GABA…
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Highly Cited
1966
Highly Cited
1966
Desoxycorticosterone Secretion Rates in Hyperadrenocorticism1
M. G. Crane
,
J. J. Harris
1966
Corpus ID: 72177990
Twelve patients with hyperadrenocorticism have been presented, 3 with primary aldosteronism and 9 with Cushing's syndrome. Three…
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