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procollagen-lysine 5-dioxygenase activity
Known as:
protocollagen lysine hydroxylase activity
, protocollagen lysine dioxygenase activity
, procollagen-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating)
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Catalysis of the reaction: procollagen L-lysine + 2-oxoglutarate + O2 = procollagen 5-hydroxy-L-lysine + succinate + CO2. [EC:1.14.11.4]
National Institutes of Health
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2 relations
Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase
peptidyl-lysine 5-dioxygenase activity
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1997
1997
A common duplication in the lysyl hydroxylase gene of patients with Ehlers Danlos syndrome type VI results in preferential stimulation of lysyl hydroxylase activity and mRNA by hydralazine.
H. Yeowell
,
L. Walker
,
S. Murad
,
S. Pinnell
Archives of Biochemistry and Biophysics
1997
Corpus ID: 9186118
Patients with Ehlers Danlos Syndrome type VI (EDS VI) are biochemically characterized by a deficiency of lysyl hydroxylase (LH…
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1995
1995
Rat lysyl hydroxylase: molecular cloning, mRNA distribution and expression in a baculovirus system.
L. C. Armstrong
Biochimica et Biophysica Acta
1995
Corpus ID: 31613570
1994
1994
Minimum structural requirements for minoxidil inhibition of lysyl hydroxylase in cultured fibroblasts.
S. Murad
,
L. Walker
,
S. Tajima
,
S. Pinnell
Archives of Biochemistry and Biophysics
1994
Corpus ID: 20093501
The structural features of minoxidil contributing to its inhibitory effect on lysyl hydroxylase in cultured fibroblasts were…
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1992
1992
Structure-activity relationship of minoxidil analogs as inhibitors of lysyl hydroxylase in cultured fibroblasts.
S. Murad
,
M. Tennant
,
S. Pinnell
Archives of Biochemistry and Biophysics
1992
Corpus ID: 30033863
1985
1985
Serum stimulation of lysyl hydroxylase activity in cultured human skin fibroblasts.
S. Murad
,
A. Sivarajah
,
S. Pinnell
Connective Tissue Research
1985
Corpus ID: 27232063
In the absence of ascorbic acid, confluent human skin fibroblasts incubated in 0.5% serum-supplemented medium had one-third of…
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1981
1981
The use of a tritium release assay to measure 6-N-trimethyl-L-lysine hydroxylase activity: synthesis of 6-N-[3-3H]trimethyl-DL-lysine.
R. Stein
,
S. Englard
Analytical Biochemistry
1981
Corpus ID: 37852966
1976
1976
Lysyl hydroxylase. Further purification and characterization of the enzyme from chick embryos and chick embryo cartilage.
L. Ryhänen
Biochimica et Biophysica Acta
1976
Corpus ID: 6316837
Highly Cited
1974
Highly Cited
1974
Collagen biosynthesis. Characterization of subcellular fractions from embyonic chick fibroblasts and the intracellular localization of protocollagen prolyl and protocollagen lysyl hydroxylases.
R. Harwood
,
M. E. Grant
,
D. Jackson
Biochemical Journal
1974
Corpus ID: 45465528
1. Subcellular fractions of freshly isolated matrix-free embryonic chick tendon and sternal cartilage cells have been…
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1974
1974
Developmental changes in protocollagen lysyl hydroxylase activity in the chick embryo.
L. Ryhänen
,
K. Kivirikko
Biochimica et Biophysica Acta
1974
Corpus ID: 19589690
1973
1973
Assay of protocollagen lysyl hydroxylase activity in the skin of human subjects and changes in the activity with age.
Henrik Anttinen
,
Sakari Orava
,
Lasse Ryhänen
,
Kari I. Kivirikko
Clinica chimica acta; international journal of…
1973
Corpus ID: 30568877
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