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oxcarbazepine

Known as: oxcarbazepine [Chemical/Ingredient], oxcarbazepine substance, 10,11-Dihydro-10-oxo-5H-dibenz(b,F)azepine-5-carboxamide 
A dibenzazepine carboxamide derivative with an anticonvulsant property. As a prodrug, oxcarbazepine is converted to its active metabolite, 10… 
National Institutes of Health

Related topics

Related topics

16 relations

Broader (4)

AnticonvulsantsCarbamazepineCytochrome P-450 CYP3A InducersVoltage-Gated Sodium Channel Blockers
Antiepileptic AgentsDrug AllergyEpilepsies, PartialEpilepsy

Narrower (2)

TimoxTrileptal

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Anticonvulsants in the Treatment of Major Depressive Disorder: An Overview
&NA; Major depressive disorder (MDD) is highly prevalent, potentially disabling, and sometimes fatal. Antidepressants (ADs) have… 
2008
2008
Inhibition of human aromatase complex (CYP19) by antiepileptic drugs.
2007
2007
Furosemide potentiates the anticonvulsant action of valproate in the mouse maximal electroshock seizure model
Review
2006
Review
2006
New generation anticonvulsants for the treatment of epilepsy in children
SummaryIn the last 12 years, 10 new anticonvulsants have been approved by the U.S. Food and Drug Administration and. as a result… 
Review
2001
Review
2001
Oxcarbazepine in the Treatment of Epilepsy
Oxcarbazepine is a new antiepileptic drug (AED) that has been registered in more than 50 countries worldwide since 1990 and… 
Highly Cited
1994
Highly Cited
1994
A double-blind, placebo-controlled interaction study between oxcarbazepine and carbamazepine, sodium valproate and phenytoin in epileptic patients.
1. The effect of carbamazepine (CBZ), sodium valproate (VPA) and phenytoin (PHT) on the pharmacokinetics of oxcarbazepine (OXC… 
Highly Cited
1993
Highly Cited
1993
The pharmacokinetics of oxcarbazepine and its active metabolite 10-hydroxy-carbazepine in healthy subjects and in epileptic patients treated with phenobarbitone or valproic acid.
The kinetics of oxcarbazepine (OXC) and its active metabolite 10-hydroxy-carbazepine (10-OH-CZ) after a single oral OXC dose (600… 
1990
1990
Metabolic characteristics of oxcarbazepine (®trileptal) and their beneficial implications for enzyme induction and drug interactions.
Hepatic oxygenases of the cytochrome P-450 family play a major role in the clearance of various anti-epileptic drugs. These… 
Highly Cited
1983
Highly Cited
1983
Pharmacokinetics of 10‐OH‐carbazepine, the main metabolite of the antiepileptic oxcarbazepine, from serum and saliva concentrations
After administration of 600 mg of the antiepileptic oxcarbazepine to 7 healthy volunteers, serum and stimulated saliva samples… 
1974
1974
VARIATION IN SUSCEPTIBILITY OF A HUMAN LYMPHOID CELL LINE TO IMMUNE LYSIS DURING THE CELL CYCLE
Cultured human lymphoid cells RPMI 8866 at different stages of their growth cycle vary in their susceptibility to lysis by rabbit… 
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