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fosfluconazole
Known as:
1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)-1-[(1H-1,2,4-triazol-1-yl)methyl]ethyl dihydrogen phosphate
National Institutes of Health
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Related topics
Related topics
4 relations
Broader (3)
14-alpha Demethylase Inhibitors
Fluconazole
Organophosphates
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Case of cryptococcal choroiditis in adult with T-cell leukemia/lymphoma.
Wataru Yamada
,
H. Yamada
,
+4 authors
K. Ishida
Journal of Infection and Chemotherapy
2019
Corpus ID: 51864257
2014
2014
Pulmonary cryptococcosis presenting with a large cavity
S. Morita
,
T. Shirai
,
K. Asada
,
M. Fujii
,
Makoto Suzuki
,
T. Suda
Respirology Case Reports
2014
Corpus ID: 18332024
A 78‐year‐old woman who was receiving corticosteroids for rheumatoid arthritis was admitted to our hospital to have her fever…
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2010
2010
Comparison and optimization of RP-HPLC methods foranalysis of fosfluconazole and its related substances
Hu Chang-qin
2010
Corpus ID: 98937037
Objective:To compare and optimize 3 testing methods for analysis of fosfluconazole and its related substances to determine which…
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2009
2009
[Comparison of micafungin and fosfluconazole as prophylaxis for invasive fungal infection during neutropenia in children undergoing chemotherapy and hematopoietic stem cell transplantation].
A. Sawada
,
N. Sakata
,
+11 authors
K. Kawa
[Rinsho ketsueki] The Japanese journal of…
2009
Corpus ID: 36072227
Invasive fungal infection (IFI) is a serious complication of chemotherapy for hematological malignancies and autologous…
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2009
2009
Fosfluconazole for Antifungal Prophylaxis in Very Low Birth Weight Infants
Daijiro Takahashi
,
Tomohiko Nakamura
,
+5 authors
A. Shirahata
International Journal of Pediatrics
2009
Corpus ID: 3163770
We conducted a retrospective case series study to evaluate the safety of fosfluconazole prophylaxis for preventing invasive…
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2005
2005
Pharmacokinetics of fluconazole and fosfluconazole after intraperitoneal administration to peritoneal dialysis rats.
Takahiko Aoyama
,
K. Ogata
,
+5 authors
Y. Matsumoto
Drug Metabolism and Pharmacokinetics
2005
Corpus ID: 35056317
Fluconazole (FLCZ) is an antifungal agent that is efficacious in the treatment of fungal peritonitis. Fosfluconazole (F-FLCZ) is…
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2004
2004
Pharmacokinetics and Safety of Fosfluconazole after Single Intravenous Bolus Injection in Healthy Male Japanese Volunteers
S. Sobue
,
K. Sekiguchi
,
K. Shimatani
,
Keith Tan
Journal of clinical pharmacology
2004
Corpus ID: 38560920
This was a single blind, placebo‐controlled, escalating single‐dose, three‐period crossover study using two subject cohorts to…
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2004
2004
Comparison of the pharmacokinetics of fosfluconazole and fluconazole after single intravenous administration of fosfluconazole in healthy Japanese and Caucasian volunteers
S. Sobue
,
Keith Tan
,
L. Shaw
,
G. Layton
,
R. Hust
European Journal of Clinical Pharmacology
2004
Corpus ID: 32546323
ObjectivesTo investigate the bioavailability of fluconazole (FLCZ) from fosfluconazole (phosphate pro-drug of FLCZ) and to…
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2004
2004
The effects of renal impairment on the pharmacokinetics and safety of fosfluconazole and fluconazole following a single intravenous bolus injection of fosfluconazole.
S. Sobue
,
Keith Tan
,
G. Layton
,
V. Leclerc
,
A. Weil
British Journal of Clinical Pharmacology
2004
Corpus ID: 601180
AIMS Fosfluconazole is a phosphate prodrug of fluconazole (FLCZ). This study was conducted to investigate the effect of renal…
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Review
2004
Review
2004
[Nonclinical studies and clinical studies on fosfluconazole, a triazole antifungal agent (Prodif)].
Y. Kawakami
,
K. Nagino
,
Keisuke Shinkai
,
S. Sobue
,
M. Abe
,
J. Ishiko
Nihon yakurigaku zasshi. Folia pharmacologica…
2004
Corpus ID: 41236680
Fosfluconazole is a phosphate prodrug of fluconazole that has been developed to reduce the volume of fluid required to administer…
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