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eosinophil differentiation
Known as:
eosinophil cell differentiation
The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil. [GOC:add, GOC:mah]
National Institutes of Health
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2004
2004
Deletion of the major GATA1 enhancer HS 1 does not affect eosinophil GATA1 expression and eosinophil differentiation.
B. Guyot
,
Verónica Valverde-Garduño
,
C. Porcher
,
P. Vyas
Blood
2004
Corpus ID: 23843938
Expression of the myeloid transcription factor GATA1 is required for early stages of eosinophil differentiation. Defining…
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Highly Cited
2003
Highly Cited
2003
Signal transducer and activator of transcription 5a (STAT5a) is required for eosinophil differentiation of human cord blood-derived CD34+ cells.
M. Buitenhuis
,
B. Baltus
,
J. Lammers
,
P. Coffer
,
L. Koenderman
Blood
2003
Corpus ID: 45712681
Signal transducers and activators of transcription (STATs) have been reported to play a critical role in the differentiation of…
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2002
2002
Lyn Tyrosine Kinase Is Important for IL-5-Stimulated Eosinophil Differentiation1
S. Stafford
,
C. Lowell
,
S. Sur
,
R. Alam
Journal of Immunology
2002
Corpus ID: 6494017
IL-5 plays a pivotal role in growth and differentiation of eosinophils. The signal transduction mechanism of IL-5Rα is largely…
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Highly Cited
1998
Highly Cited
1998
Distinct C/EBP functions are required for eosinophil lineage commitment and maturation.
C. Nerlov
,
K. McNagny
,
G. Döderlein
,
E. Kowenz-Leutz
,
T. Graf
Genes & Development
1998
Corpus ID: 32533102
Hematopoietic differentiation involves the commitment of multipotent progenitors to a given lineage, followed by the maturation…
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1995
1995
Effect of IL‐4 and interferon‐gamma (IFN‐γ) on IL‐3‐ and IL‐5‐induced eosinophil differentiation from human cord blood mononuclear cells
K. Ochiai
,
I. Iwamoto
,
H. Takahashi
,
S. Yoshida
,
H. Tomioka
,
S. Yoshida
Clinical and Experimental Immunology
1995
Corpus ID: 36689716
IL‐4 and IFN‐γ positively and negatively regulate allergic inflammation. To determine the regulatory mechanisms of eosinopoiesis…
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1992
1992
Aspergillus antigen-induced eosinophil differentiation in a murine model
P. S. Murali
,
G. Dai
,
Anoopa Kumar
,
Jordan N. Fink
,
V. Kurup
Infection and Immunity
1992
Corpus ID: 24629294
Eosinophilia is a prominent feature of the cellular response in allergic and parasitic diseases. Allergic bronchopulmonary…
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Highly Cited
1990
Highly Cited
1990
Characterization of a receptor for interleukin 5 on human eosinophils: variable expression and induction by granulocyte/macrophage colony- stimulating factor
Junichi Chihara
,
J. Plumas
,
+4 authors
Monique Capron
Journal of Experimental Medicine
1990
Corpus ID: 2621031
Interleukin 5 (IL-5) acts on eosinophil differentiation and activation, suggesting the existence of a membrane receptor for IL-5…
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1986
1986
Detection of eosinophil differentiation factor and its relationship to eosinophilia in Mesocestoides corti-infected mice.
M. Strath
,
C. Sanderson
Experimental Hematology
1986
Corpus ID: 33820804
Eosinophil differentiation activity has been identified using a simple assay to detect eosinophil differentiation in vitro. Two…
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Highly Cited
1985
Highly Cited
1985
Identification of a lymphokine that stimulates eosinophil differentiation in vitro. Its relationship to interleukin 3, and functional properties of eosinophils produced in cultures
C. Sanderson
,
D. Warren
,
M. Strath
Journal of Experimental Medicine
1985
Corpus ID: 11099539
Factors stimulating eosinophil differentiation in vitro have been studied by means of a liquid bone marrow culture system in…
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Highly Cited
1985
Highly Cited
1985
Production of a T-cell hybrid producing a lymphokine stimulating eosinophil differentiation.
D. Warren
,
C. Sanderson
Immunology
1985
Corpus ID: 21443968
Spleen cells from mice undergoing a parasite-induced eosinophilia were fused with an azaguanine-resistant subline of the thymoma…
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