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desmethoxyyangonin

National Institutes of Health

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Pyrones

Papers overview

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2017
2017
(+)- and (-)-Ecarlottones, Uncommon Chalconoids from Fissistigma latifolium with Pro-Apoptotic Activity.
Four new compounds, (+)- and (-)-ecarlottone (1), (±)-fislatifolione (5), (±)-isofislatifolione (6), and (±)-fislatifolic acid (7… 
2009
2009
High-performance liquid chromatography assays for desmethoxyyangonin, methysticin, kavain and their microsomal metabolites.
Three novel, simple and reproducible high-performance liquid chromatography quantitative assays with UV detection were developed… 
2006
2006
Kavalactones fail to inhibit alcohol dehydrogenase in vitro.
2005
2005
Determination of kava lactones in food supplements by liquid chromatography-atmospheric pressure chemical ionisation tandem mass spectrometry.
2005
2005
Determination of six kavalactones in dietary supplements and selected functional foods containing Piper methysticum by isocratic liquid chromatography with internal standard.
Kava (Piper methysticum) dietary products have been sold worldwide for treatment of nervous anxiety, tension, and restlessness… 
2005
2005
Superheated water chromatography-nuclear magnetic resonance spectroscopy of kava lactones.
Three kava lactone constituents of Piper methysticum, namely, kawain, methysticin and desmethoxyyangonin, have been separated and… 
2004
2004
DESMETHOXYYANGONIN AND DIHYDROMETHYSTICIN ARE TWO MAJOR PHARMACOLOGICAL KAVALACTONES WITH MARKED ACTIVITY ON THE INDUCTION OF CYP3A23
Kava kava (Piper methysticum), an herbal remedy, is widely used for the treatment of mild to moderate cases of anxiety. The… 
2004
2004
Kava does not display metabolic toxicity in a homogeneous cellular assay.
To determine whether kava (Kava kava, 'Awa, Yaqona, Piper methysticum Forst.), the popular herbal product associated recently… 
2001
2001
Anxiolytic effects of kava extract and kavalactones in the chick social separation-stress paradigm
Abstract. Rationale: Piper methysticum extract (kava kava) possesses numerous therapeutic properties, but it is unknown which of… 
1997
1997
Contribution to the quantitative and enantioselective determination of kavapyrones by high-performance liquid chromatography on ChiraSpher NT material.
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