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daunorubicin biosynthetic process
Known as:
daunorubicin biosynthesis
, daunorubicin anabolism
, daunorubicin synthesis
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The chemical reactions and pathways resulting in the formation of daunorubicin. [GOC:TermGenie, GOC:yaf, PMID:7601857, UniPathway:UPA00054]
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
Isolation and characterization of stable mutants ofStreptomyces peucetius defective in daunorubicin biosynthesis
K. S. Vetrivel
,
K. Dharmalingam
Journal Genetika
2001
Corpus ID: 33303011
Daunorubicin and its derivative doxorubicin are antitumour anthracycline antibiotics produced byStreptomyces peucetius. In this…
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2001
2001
Purification, cloning, and DNA sequence analysis of a chitinase from an overproducing mutant of Streptomyces peucetius defective in daunorubicin biosynthesis.
K. S. Vetrivel
,
S. K. Pandian
,
U. Chaudhary
,
K. Dharmalingam
Canadian Journal of Microbiology (print)
2001
Corpus ID: 13242398
Extracellular chitinases of Streptomyces peucetius and a chitinase overproducing mutant, SPVI, were purified to homogeneity by…
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2000
2000
The dnrO gene encodes a DNA-binding protein that regulates daunorubicin production in Streptomyces peucetius by controlling expression of the dnrN pseudo response regulator gene.
S. Otten
,
C. Olano
,
C. Hutchinson
Microbiology
2000
Corpus ID: 22775809
The dnrO gene is located adjacent to and divergently transcribed from the response regulator gene, dnrN, that activates the…
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2000
2000
Isolation of a chitinase overproducing mutant of Streptomyces peucetius defective in daunorubicin biosynthesis.
K. S. Vetrivel
,
K. Dharmalingam
Canadian Journal of Microbiology (print)
2000
Corpus ID: 28418147
Streptomyces peucetius, producer of the antitumor anthracycline antibiotic daunorubicin, was mutagenized, and mutants defective…
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2000
2000
Streptomyces peucetius defective in daunorubicin biosynthesis
K. S. Vetrivel
,
K. Dharmalingam
2000
Corpus ID: 88244674
Streptomyces peucetius, producer of the antitumor anthracycline antibiotic daunorubicin, was mutagenized, and mutants defective…
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Highly Cited
1999
Highly Cited
1999
The Streptomyces peucetius dpsC Gene Determines the Choice of Starter Unit in Biosynthesis of the Daunorubicin Polyketide
Wuli Bao
,
P. Sheldon
,
E. Wendt-Pienkowski
,
C. Hutchinson
Journal of Bacteriology
1999
Corpus ID: 21802212
ABSTRACT The starter unit used in the biosynthesis of daunorubicin is propionyl coenzyme A (CoA) rather than acetyl-CoA, which is…
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Highly Cited
1996
Highly Cited
1996
The DnrN protein of Streptomyces peucetius, a pseudo-response regulator, is a DNA-binding protein involved in the regulation of daunorubicin biosynthesis
Kaoru Furuya
,
C. Hutchinson
Journal of Bacteriology
1996
Corpus ID: 7885034
DnrN, a protein essential for the transcription of the dnrI gene, which in turn activates transcription of the daunorubicin…
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Highly Cited
1996
Highly Cited
1996
Purification and characterization of the DNA‐binding protein DnrI, a transcriptional factor of daunorubicin biosynthesis in Streptomyces peucetius
Li Tang
,
A. Grimm
,
Ying‐Xin Zhang
,
C. Hutchinson
Molecular Microbiology
1996
Corpus ID: 27620238
The DnrI protein, essential for the biosynthesis of daunorubicin in Streptomyces peucetius, was purified almost to homogeneity…
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Highly Cited
1995
Highly Cited
1995
Cloning and characterization of the Streptomyces peucetius dnrQS genes encoding a daunosamine biosynthesis enzyme and a glycosyl transferase involved in daunorubicin biosynthesis
S. Otten
,
X. Liu
,
J. Ferguson
,
C. Hutchinson
Journal of Bacteriology
1995
Corpus ID: 41766589
The dnrQS genes from the daunorubicin producer Streptomyces peucetius were characterized by DNA sequencing, complementation…
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1993
1993
Nucleotide sequence analysis of five putative Streptomyces griseus genes, one of which complements an early function in daunorubicin biosynthesis that is linked to a putative gene cluster involved in…
H. Krügel
,
G. Schumann
,
F. Hänel
,
G. Fiedler
Molecular and General Genetics MGG
1993
Corpus ID: 20597718
Sequence analysis of the lkmB region of the daunorubicin biosynthetic gene cluster of Streptomyces griseus JA3933 revealed two…
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