copper transporter 1
National Institutes of Health
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Background: Copper transporter 1 (CTR1) is a critical determinant of the uptake and cytotoxic effect of the platinum drugs…
Platinum drugs are widely used in the treatment of various solid tumors, but their resistance to platinum is the most significant…
Background: Neuroblastoma is an aggressive childhood cancer that is poorly responsive to therapy. Moreover, survivors experience…
Adding platinum drugs to anthracycline/taxane (ANC-Tax)-based neoadjuvant chemotherapy (NAC) improves pathological complete…
Copper transporter 1 (CTR1) represents an important determinant of cisplatin resistance. A series of 35 semi-substituted steroids…
OBJECTIVE
To investigate the mechanism of the development of cisplatin resistance in a human esophageal squamous carcinoma cell…