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anterior neuropore closure

The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube… 
National Institutes of Health

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neuropore closure

Papers overview

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2019
2019
Mouse Whole Embryo Culture.
The embryotoxicity associated with exposure to exogenous compounds such as drugs and environmental chemicals can be assessed… 
2015
2015
Embryonic catalase protects against ethanol embryopathies in acatalasemic mice and transgenic human catalase-expressing mice in embryo culture.
2014
2014
Deficient DNA repair exacerbates ethanol-initiated DNA oxidation and embryopathies in ogg1 knockout mice: gender risk and protection by a free radical spin trapping agent
Reactive oxygen species (ROS) have been implicated in the teratogenicity of alcohol (ethanol, EtOH). To determine the involvement… 
2003
2003
Antagonism of hypervitaminosis A-induced anterior neural tube closure defects with a methyl-donor deficiency in murine whole-embryo culture.
The interaction of a dietary excess of vitamin A (retinoid) and deficiency of methyl-donor compounds was examined in murine early… 
2000
2000
Hairy backs, tails and dimples
The term ‘spinal dysraphism’ encompasses a hetero-geneous group of congenital anomalies of spinal corddevelopment characterized… 
1994
1994
Evidence for embryonic peroxidase-catalyzed bioactivation and glutathione-dependent cytoprotection in phenytoin teratogenicity: modulation by eicosatetraynoic acid and buthionine sulfoximine in…
Phenytoin teratogenicity may result from embryonic, peroxidase-catalyzed bioactivation of phenytoin to a toxic reactive free… 
1989
1989
Abnormal neurulation induced by 7-hydroxy-2-acetylaminofluorene and acetaminophen: evidence for catechol metabolites as proximate dysmorphogens.
1989
1989
Phenytoin embryotoxicity: role of enzymatic bioactivation in a murine embryo culture model.
A murine embryo culture model was developed to study the potential contribution of enzymatic bioactivation to the teratogenicity… 
1983
1983
Early morphological abnormalities in splotch mouse embryos and predisposition to gene- and retinoic acid-induced neural tube defects.
Genetic and environmental factors contribute to an individual's neural tube defect liability. In the mouse, the gene mutation… 
1976
1976
[Diencephalic cyst--in relation to other midline dysraphism (author's transl)].
The abnormal midline cyst of diencephalic origin was termed "diencephalic cyst" by Brocklehurst in 1973. Since then, several case… 
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