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ZD 6021
Known as:
(3-cyano-N-(2-(3,4-dichlorophenyl)-4-(4-(2-(methylsulfinyl)phenyl)piperidino)butyl)-N-methyl)naphthamide
, ZD-6021
, ZD6021
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Piperidines
Sulfoxides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Occurrence and pharmacological characterization of four human tachykinin NK2 receptor variants.
I. Ahlstedt
,
Susanna Engberg
,
+8 authors
E. Lindström
Biochemical Pharmacology
2008
Corpus ID: 11257524
2007
2007
Molecular cloning, mutations and effects of NK1 receptor antagonists reveal the human-like pharmacology of gerbil NK1 receptors.
Susanna Engberg
,
I. Ahlstedt
,
+7 authors
B. von Mentzer
Biochemical Pharmacology
2007
Corpus ID: 5930207
2004
2004
Glutamate and tachykinin receptors in central sensitization of withdrawal reflexes in the decerebrated rabbit
John Harris
,
C. Joules
,
C. Stanley
,
P. Thomas
,
R. Clarke
Experimental Physiology
2004
Corpus ID: 39928044
This study assessed the involvement of NMDA and group I metabotropic glutamate receptors, and tachykinin NK1 and NK3 receptors…
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2002
2002
Design, synthesis, and SAR of tachykinin antagonists: modulation of balance in NK(1)/NK(2) receptor antagonist activity.
J. Albert
,
D. Aharony
,
+18 authors
K. Russell
Journal of Medicinal Chemistry
2002
Corpus ID: 19879722
Through optimization of compounds based on the dual NK(1)/NK(2) antagonist ZD6021, it was found that alteration of two key…
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2001
2001
Pharmacological characterization of ZD6021: a novel, orally active antagonist of the tachykinin receptors.
W. Rumsey
,
D. Aharony
,
+14 authors
K. Russell
Journal of Pharmacology and Experimental…
2001
Corpus ID: 39588526
The tachykinins, substance P, neurokinin A, and neurokinin B, have been implicated in many diseases. The present study evaluated…
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