Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 221,894,032 papers from all fields of science
Search
Sign In
Create Free Account
Sulfaphenazole
Known as:
Sulfafenazol
, N'-(1-phenylpyrazol-5-yl)sulfanilamide
, Sulfaphenylpyrazol
Expand
A long-acting sulfonamide antibiotic used in the treatment of leprosy.
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
11 relations
Narrower (3)
1-phenyl-3-methyl-5-sulfanilamidopyrazole
N4-acetylsulfaphenazole
sulfaphenazole-N2-glucuronide
Broader (1)
Anti-Infective Agents
In Blood
agonists
analogs & derivatives
antagonists & inhibitors
Expand
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Development of an in vitro drug-drug interaction assay to simultaneously monitor five cytochrome P450 isoforms and performance assessment using drug library compounds.
Michael A. Zientek
,
Howard Miller
,
+7 authors
Douglas Burdette
Journal of pharmacological and toxicological…
2008
Corpus ID: 11289412
Highly Cited
2005
Highly Cited
2005
Electrochemical characterisation of the human cytochrome P450 CYP2C9.
D. Johnson
,
B. Lewis
,
D. Elliot
,
J. Miners
,
L. Martin
Biochemical Pharmacology
2005
Corpus ID: 46458002
Highly Cited
2003
Highly Cited
2003
Characterization of the cytochrome P450 isoenzymes involved in the in vitro N-dealkylation of haloperidol.
L. Pan
,
P. Wijnant
,
C. D. de Vriendt
,
M. Rosseel
,
F. Belpaire
British Journal of Clinical Pharmacology
2003
Corpus ID: 27508987
AIMS The present study was carried out to identify the cytochrome P450 isoenzyme(s) involved in the N-dealkylation of haloperidol…
Expand
Highly Cited
2002
Highly Cited
2002
Identification of glutathione conjugates of troglitazone in human hepatocytes.
S. Prabhu
,
Andrew Fackett
,
+4 authors
Albert P. Li
Chemico-Biological Interactions
2002
Corpus ID: 9135249
Highly Cited
2000
Highly Cited
2000
Metabolism of 3-methylindole by porcine liver microsomes: responsible cytochrome P450 enzymes.
Gonzalo J. Diaz
,
E. Squires
Toxicological Sciences
2000
Corpus ID: 45453392
The role of different cytochrome P450 enzymes on the metabolism of 3-methylindole (3MI) was investigated using selective chemical…
Expand
Highly Cited
1995
Highly Cited
1995
N-Hydroxylation of dapsone by multiple enzymes of cytochrome P450: implications for inhibition of haemotoxicity.
H. Gill
,
M. Tingle
,
B. Park
British Journal of Clinical Pharmacology
1995
Corpus ID: 37168698
1. The adverse reactions associated with the administration of dapsone are believed to be caused by metabolism to its…
Expand
Highly Cited
1993
Highly Cited
1993
Human liver microsomal metabolism of the enantiomers of warfarin and acenocoumarol: P450 isozyme diversity determines the differences in their pharmacokinetics
J. Hermans
,
H. Thijssen
British Journal of Pharmacology
1993
Corpus ID: 39428051
1 To explain the large differences in (the stereoselectivity of) the clearances of the enantiomers of warfarin and acenocoumarol…
Expand
Highly Cited
1979
Highly Cited
1979
Drugs causing fixed eruptions
J. Pasricha
British Journal of Dermatology
1979
Corpus ID: 12281538
Forty patients having fixed drug eruptions were subjected to provocation tests. Twelve patients failed to complete the…
Expand
Highly Cited
1977
Highly Cited
1977
The chemotherapy of rodent malaria, XXVII. Studies on mefloquine (WR 142,490).
W. Peters
,
R. Howells
,
J. Portus
,
B. Robinson
,
S. Thomas
,
D. Warhurst
Annals of Tropical Medicine and Parasitology
1977
Corpus ID: 12359469
Mefloquine (WR 142,490) is a potent blood schizontocide active against drug-sensitive and drug-resistant lines of Plasmodium…
Expand
Highly Cited
1971
Highly Cited
1971
The binding of sulfaphenazole to fetal, neonatal, and adult human plasma albumin
C. Chignell
,
E. Vesell
,
D. K. Starkweather
,
C. Berlin
Clinical pharmacology and therapy
1971
Corpus ID: 13395726
In man, sulfaphenazole has a lower affinity for the albumin of the fetus and neonate than for that of the adult. Removal of bound…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE