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Second Messenger Systems

Known as: Messengers, Intracellular Second, messenger second, Second Messengers of Signal Transduction 
Systems in which an intracellular signal is generated in response to an intercellular primary messenger such as a hormone or neurotransmitter. They… 
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (8)

1,2-diacylglycerolCalciumCyclic AMPCyclic GMP

Broader (2)

Binding SitesSignal Transduction
Cell Communicationaspects of radiation effectsphysiological aspects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
PtdIns5P regulation through evolution: roles in membrane trafficking?
Review
2006
Review
2006
Estrogen receptor alpha: impact of ligands on intracellular shuttling and turnover rate in breast cancer cells.
Estrogen receptors (alpha and beta) are members of the steroid/thyroid nuclear receptors superfamily of ligand-dependent… 
Highly Cited
2002
Highly Cited
2002
Development of novel EDG3 antagonists using a 3D database search and their structure-activity relationships.
Sphingosine-1-phosphate (S1P) is an intracellular second messenger and an extracellular mediator through endothelial… 
Highly Cited
1998
Highly Cited
1998
Receptor that leaves a sour taste in the mouth
The ability to detect taste stimuli results from the activation of taste receptors located in taste-bud cells. There are several… 
Highly Cited
1996
Highly Cited
1996
Spatio-temporal dynamics of cyclic AMP signals in an intact neural circuit
THE functional properties of neuronal networks can be reconfigured by a variety of modulatory neurotransmitters, which may alter… 
Highly Cited
1994
Highly Cited
1994
Functional coupling of SSTR4, a major hippocampal somatostatin receptor, to adenylate cyclase inhibition, arachidonate release and activation of the mitogen-activated protein kinase cascade.
Highly Cited
1993
Highly Cited
1993
Extracellular cAMP is sufficient to restore developmental gene expression and morphogenesis in Dictyostelium cells lacking the aggregation adenylyl cyclase (ACA).
Cell movement and cell-type-specific gene expression during Dictyostelium development are regulated by cAMP, which functions both… 
Highly Cited
1992
Highly Cited
1992
Activation of a Gi protein in mouse sperm membranes by solubilized proteins of the zona pellucida, the egg's extracellular matrix.
Review
1987
Review
1987
Transmembrane Signals and Intracellular “Second Messengers” in the Regulation of Quiescent B‐Lymphocyte Activation
The physiology of B lymphocytes is regulated by antigen, a large number of cellderived soluble molecules {cytokines) and perhaps… 
Highly Cited
1985
Highly Cited
1985
Neural and molecular mechanisms underlying information storage in Aplysia: implications for learning and memory
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