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Medigoxin
Known as:
Medigoxin [Chemical/Ingredient]
, beta-Methyldigoxin
, Card-20(22)-enolide, 3-((O-2,6-dideoxy-4-O-methyl-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-12,14-dihydroxy-, (3beta,5beta,12beta)-
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A semisynthetic digitalis glycoside with the general properties of DIGOXIN but more rapid onset of action. Its cardiotonic action is prolonged by its…
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National Institutes of Health
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Related topics
Related topics
14 relations
Broader (4)
Anti-Arrhythmia Agents
Cardiotonic Agents
Enzyme Inhibitors
Methyldigoxin
Narrower (3)
Bemecor
Lanitop
Medixin
In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Role of organic anion transporting polypeptide 2 in pharmacokinetics of digoxin and beta-methyldigoxin in rats.
Sachiyo Funakoshi
,
T. Murakami
,
R. Yumoto
,
Yoshie Kiribayashi
,
M. Takano
Journal of Pharmacy and Science
2005
Corpus ID: 32207069
Recently, we found that potent P-glycoprotein (P-gp) inhibitors, such as verapamil and cyclosporin A, markedly modulated the…
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1989
1989
Semicontinuous cultivation of Digitalis lanata cells: Production of β‐methyldigoxin in a 300‐L airlift bioreactor
E. Reinhard
,
W. Kreis
,
U. Barthlen
,
U. Helmbold
Biotechnology and Bioengineering
1989
Corpus ID: 42351960
Selected Digitalis lanata cell lines cultivated in 1‐L shake flasks or 20‐L airlift bioreactors converted β‐methyldigitoxin into…
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1989
1989
Determination of beta-methyldigoxin and its metabolites by high-performance liquid chromatography and fluorescence polarization immunoassay.
H. Nakashima
,
K. Tsutsumi
,
M. Hashiguchi
,
Y. Kumagai
,
A. Ebihara
Journal of Chromatography A
1989
Corpus ID: 43503659
1981
1981
Inhibitory effect of anoxia on reperfusion- and digitalis-induced ventricular tachyarrhythmias.
P. Carbonin
,
M. Di Gennaro
,
R. Valle
,
A. Weisz
American Journal of Physiology
1981
Corpus ID: 22501920
In the isolated rat heart, anoxia or ischemia do not induce important ventricular tachyarrhythmias (VTAs). During the 1st min of…
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1981
1981
Pharmacokinetics of Metildigoxin and Digoxin in Geriatric Patients with Normal and Elevated Serum Creatinine Levels
B. Kaufmann
,
A. Olcay
,
W. Schaumann
,
W. Teufel
,
W. Weib
Clinical Pharmacokinetics
1981
Corpus ID: 20696622
SummaryThe pharmacokinetics of digoxin and metildigoxin were investigated in geriatric patients on maintenance treatment. Minimum…
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1979
1979
Tissue Distribution and Elimination of Digoxin and Methyldigoxin After Single and Multiple Doses in Dogs
J. Kuhlmann
,
N. Rietbrock
,
B. Schnieders
Journal of Cardiovascular Pharmacology
1979
Corpus ID: 39681851
Summary Glycoside concentrations in plasma and various tissues of dogs were determined after a single and repeated intravenous…
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1978
1978
Comparison of digoxin and medigoxin in normal subjects.
Hayward Rp
,
H. Greenwood
,
J. Hamer
British Journal of Clinical Pharmacology
1978
Corpus ID: 25830727
1 The properties of a recently introduced digitalis glycoside, 4-beta-methyl digoxin (medigoxin) were compared to those of a…
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1978
1978
Effect of Digoxin and Diuretics on High Altitude Left Ventricular Dysfunction
V. Balasubramanian
,
A. Behl
,
G. Das
,
A. Wadhwa
,
O. Mathew
,
R. S. Hoon
Circulation
1978
Corpus ID: 5839708
SUMMARYSystolic time intervals, stroke volume, cardiac output and (dZ/dt)/RZ index were serially estimated in 51 normal healthy…
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Review
1977
Review
1977
Pharmacokinetics of beta-methyldigoxin in healthy humans II: Oral studies and bioavailability.
P. Hinderling
,
E. R. Garrett
,
R. Wester
Journal of Pharmacy and Science
1977
Corpus ID: 24107303
The pharmacokinetics of orally administered aqueous 3H-beta-methyldigoxin solutions were studied at two dose levels, 0.3 and 0.6…
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1976
1976
Bioavailability and pharmacokinetics of β- methyldigoxin after multiple oral and intravenous doses
N. Rietbrock
,
J. Guggenmos
,
J. Kuhlmann
,
U. Hess
European Journal of Clinical Pharmacology
1976
Corpus ID: 19684832
SummaryTo obtain true half lives, glycoside elimination from six healthy subjects was studied for 14 days after multiple…
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