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Malate-Aspartate Shuttle Pathway

Known as: malate:aspartate shuttle, malate/aspartate shuttle, malate aspartate shuttle 
The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this… 
National Institutes of Health

Related topics

Related topics

2 relations
Cytoplasmic Aspartate Aminotransferase

Broader (1)

respiratory electron transport chain process

Papers overview

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Highly Cited
2012
Highly Cited
2012
Cytosolic Ca2+ regulates the energization of isolated brain mitochondria by formation of pyruvate through the malate-aspartate shuttle.
The glutamate-dependent respiration of isolated BM (brain mitochondria) is regulated by Ca2+(cyt) (cytosolic Ca2+) (S0.5=225±22… 
2005
2005
Correlation between myocardial malate/aspartate shuttle activity and EAAT1 protein expression in hyper- and hypothyroidism.
In the heart, elevated thyroid hormone leads to upregulation of metabolic pathways associated with energy production and… 
Highly Cited
1999
Highly Cited
1999
Alterations in the glycolytic and glutaminolytic pathways after malignant transformation of rat liver oval cells
Oval cells are liver epithelial cells that proliferate during the early stages of hepatocarcinogenesis induced by a variety of… 
Highly Cited
1991
Highly Cited
1991
Glutamate Oxaloacetate Transaminase in Pea Root Nodules : Participation in a Malate/Aspartate Shuttle between Plant and Bacteroid.
Glutamate oxaloacetate transaminase (l-glutamate: oxaloacetate aminotransferase, EC 2.6.1.1 [GOT]), a key enzyme in the flow of… 
Highly Cited
1990
Highly Cited
1990
Redox interactions between catalase and alcohol dehydrogenase pathways of ethanol metabolism in the perfused rat liver.
1986
1986
Depression of alcohol dehydrogenase activity in rat hepatocyte culture by dihydrotestosterone.
1979
1979
Quantitative evaluation of the activity of the malate-aspartate shuttle in Ehrlich ascites tumor cells.
Abstract The ability of the malate-aspartate shuttle and of the lactate dehydrogenase reaction to reoxidize glycolytic reduced… 
1978
1978
Activity and androgenic control of enzymes associated with the tricarboxylic acid cycle, lipid oxidation and mitochondrial shuttles in the epididymis and epididymal spermatozoa of the rat.
1. Enzyme activities (units/g wet wt.) were determined in the caput and cauda epididymidis and in epididymal spermatozoa of the… 
Highly Cited
1977
Highly Cited
1977
Transfer and reoxidation of reducing equivalents as the rate-limiting steps in the oxidation of ethanol by liver cells isolated from fed and fasted rats.
1976
1976
Suppression of the mitochondrial oxidation of (-)-palmitylcarnitine by the malate-aspartate and alpha-glycerophosphate shuttles.
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