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Ligase Chain Reaction
Known as:
Reactions, Ligase Chain
, Reaction, Ligase Chain
, Ligase Chain Reactions
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A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a…
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National Institutes of Health
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Related topics
Related topics
2 relations
Polymerase Chain Reaction
standards characteristics
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Simultaneous detection of recombinant DNA segments introduced into genetically modified crops with multiplex ligase chain reaction coupled with multiplex polymerase chain reaction.
J. Mano
,
Taichi Oguchi
,
+4 authors
K. Kitta
Journal of Agricultural and Food Chemistry
2009
Corpus ID: 20298834
We developed a multiplex polymerase chain reaction (PCR)-multiplex ligase chain reaction (LCR) (MPCR-MLCR) technique as a novel…
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2004
2004
Real-Time Gap Ligase Chain Reaction
S. Harden
,
David C. Thomas
,
+5 authors
D. Sidransky
Clinical Cancer Research
2004
Corpus ID: 12936112
Purpose: We have developed a real-time semiquantitative gap ligase chain reaction for detecting p53 point mutations at low level…
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2003
2003
Detection of HLA polymorphisms by ligase detection reaction and a universal array format: a pilot study for low resolution genotyping.
C. Consolandi
,
E. Busti
,
+7 authors
G. De Bellis
Human Immunology
2003
Corpus ID: 39926313
2001
2001
Optimised sample DNA preparation for detection ofChlamydia trachomatis in synovial tissue by polymerase chain reaction and ligase chain reaction
J. Freise
,
H. Gérard
,
+5 authors
J. Kuipers
Annals of the Rheumatic Diseases
2001
Corpus ID: 1828296
OBJECTIVE Molecular biology techniques such as polymerase chain reaction (PCR) and ligase chain reaction (LCR) are routinely used…
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1999
1999
Needle-in-a-haystack detection and identification of base substitution mutations in human tissues.
V. L. Wilson
,
Q. Wei
,
+7 authors
W. Lee
Mutation research
1999
Corpus ID: 26059925
Highly Cited
1997
Highly Cited
1997
Urinary inhibitors of polymerase chain reaction and ligase chain reaction and testing of multiple specimens may contribute to lower assay sensitivities for diagnosing Chlamydia trachomatis infected…
M. Chernesky
,
D. Jang
,
+4 authors
J. Mahony
Molecular and Cellular Probes
1997
Corpus ID: 40262668
In a comparison of commercial ligase chain reaction (LCR; Abbott) and polymerase chain reaction (PCR; Roche) assays, measuring…
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1997
1997
Detection by ligase chain reaction of precore mutant of hepatitis B virus
S. Minamitani
,
S. Nishiguchi
,
T. Kuroki
,
S. Otani
,
T. Monna
Hepatology
1997
Corpus ID: 38501224
The clinical diagnosis of infection with the most common precore mutant of hepatitis B virus (HBV), that with a point mutation…
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1996
1996
Analysis of ligase chain reaction products via matrix-assisted laser desorption/ionization time-of-flight-mass spectrometry.
C. Jurinke
,
D. van den Boom
,
A. Jacob
,
K. Tang
,
R. Wörl
,
H. Köster
Analytical Biochemistry
1996
Corpus ID: 23946349
A rapid and accurate detection of ligation products generated in ligase chain reactions (LCR) by using matrix-assisted laser…
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1996
1996
Urine as a Diagnostic Specimen for the Detection of Chlamydia trachomatis in Malaysia by Ligase Chain Reaction
C. Gaydos
,
Y. Ngeow
,
Helen H. Lee
,
L. Welsh
,
Julie Johanson
,
T. Quinn
Sexually Transmitted Diseases
1996
Corpus ID: 25988857
Background and Objectives: Noninvasive urine screening for Chlamydia trachomatis infections offers a valuable public health tool…
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Review
1993
Review
1993
The ligase chain reaction in DNA-based diagnosis.
T. Laffler
,
J. Carrino
,
R. Marshall
Annales de Biologie Clinique
1993
Corpus ID: 29613082
Clinical specimens containing a suspected pathogen often have too little of the pathogen's DNA to be detected directly. It is…
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