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KAT6A/NCOA2 Fusion Protein

Known as: MYST3-NCOA2 Fusion Protein, MOZ/TIF2 Fusion Protein, Histone Acetyltransferase KAT6A/Nuclear Receptor Coactivator 2 Fusion Protein 
A fusion protein encoded by the KAT6A/NCOA2 fusion gene. This protein is comprised of the N-terminal zinc finger and histone acetylase domains of the… 
National Institutes of Health

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2 relations
Fusion GeneMOZ/TIF2 FUSION GENE

Papers overview

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2009
2009
Modulation of Androgen Receptor Transcriptional Activity
textabstractAndrogens, testosterone (T) and 5a-dihydrotestosterone (DHT), are important for male and female physiology, in… 
2007
2007
Quantitative detection of the ligand-dependent interaction between the androgen receptor and the co-activator, Tif2, in live cells using two color, two photon fluorescence cross-correlation…
Two-photon, two-color fluorescence cross-correlation spectroscopy (TPTCFCCS) was used to directly detect ligand-dependent… 
2007
2007
Childhood acute myeloid leukemia with hemophagocytosis by the blasts and inv(8)(p11q13) with MOZ-TIF2 fusion transcripts.
We describe a unique case of de novo childhood acute myeloid leukemia in which the blasts showed evidence of hemophagocytosis and… 
2006
2006
MOZ-TIF2 alters cofactor recruitment and histone modification at the RARbeta2 promoter: differential effects of MOZ fusion proteins on CBP- and MOZ-dependent activators.
MOZ-TIF2 and MOZ-CBP are leukemogenic fusion proteins associated with therapy-induced acute myeloid leukemia. These proteins are… 
2006
2006
The role of the global co-activator CREB-binding protein in transcription : a study of competitive interactions of diverse nuclear proteins with CBP
The recruitment of the histone acetyltransferases CREB binding protein (CBP) and its homologue p300, is necessary for chromatin… 
Highly Cited
2005
Highly Cited
2005
MOZ-TIF2 Inhibits Transcription by Nuclear Receptors and p53 by Impairment of CBP Function
ABSTRACT Chromosomal rearrangements associated with acute myeloid leukemia (AML) include fusions of the genes encoding the… 
2004
2004
Altered Expression Profile of Global Genes in U937 Cells Stably Transfected with a Leukemia Fusion Gene: MOZ-TIF2.
Chromosome translocations involving the monocytic leukemia zinc finger (MOZ) gene occurs often in patients with acute myeloid… 
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