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Intercalating Agents

Known as: Intercalating Agent, Intercalating Ligands, Ligands, Intercalating 
Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore… 
National Institutes of Health

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1,10-phenanthroline9-amino-6-chloro-2-methoxyacridineAcriflavineAmsacrine
Mutagensaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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Review
2005
Review
2005
Intercalation of Organic Dye Molecules into Double-stranded DNA. Part 2: The Annelated Quinolizinium Ion as a Structural Motif in DNA Intercalators†
Abstract DNA intercalators represent an important class of compounds with a high potential as DNA-targeting drugs. In this review… 
Highly Cited
2004
Highly Cited
2004
[Ru(bpy)2(L)]Cl2: luminescent metal complexes that bind DNA base mismatches.
Here we report the synthesis of luminescent ruthenium complexes that bind DNA base pair mismatches. [Ru(bpy)2(tpqp)]Cl2 (tpqp = 7… 
Highly Cited
2000
Highly Cited
2000
Structure of a photoactive rhodium complex intercalated into DNA
Intercalating complexes of rhodium(III) are strong photo-oxidants that promote DNA strand cleavage or electron transfer through… 
Highly Cited
1998
Highly Cited
1998
Immobilization of single-stranded deoxyribonucleic acid on gold electrode with self-assembled aminoethanethiol monolayer for DNA electrochemical sensor applications.
Review
1997
Review
1997
Molecular mechanisms in retrovirus DNA integration.
Highly Cited
1989
Highly Cited
1989
A premelting conformational transition in poly(dA)-Poly(dT) coupled to daunomycin binding.
Circular dichroism and UV absorbance spectroscopy were used to monitor and characterize a premelting conformational transition of… 
Highly Cited
1989
Highly Cited
1989
Sequence-specific intercalating agents: intercalation at specific sequences on duplex DNA via major groove recognition by oligonucleotide-intercalator conjugates.
An acridine derivative was covalently linked to the 5' end of a homopyrimidine oligonucleotide. Specific binding to a homopurine… 
Highly Cited
1989
Highly Cited
1989
Radiotoxicity of an 125I-labeled DNA intercalator in mammalian cells.
To explore the effect of the Auger electron emitter 125I attached to a DNA intercalator, we have synthesized 125I- and 127I… 
Review
1984
Review
1984
Physico-chemical probes of intercalation.
Highly Cited
1979
Highly Cited
1979
Binding of platinum(II) intercalation reagents to deoxyribnonucleic acid. Dependence on base-pair composition, nature of the intercalator, and ionic strength.
The DNA binding of three platinum(II) intercalation reagents has been studied and found to depend upon base composition, the… 
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