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GLI2 protein, human
Known as:
THP2 protein, human
, Tax helper protein 2, human
, TRE-binding protein 2, human
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Zinc finger protein GLI2 (1586 aa, ~168 kDa) is encoded by the human GLI2 gene. This protein plays a role in embryonic development and…
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National Institutes of Health
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Related topics
Related topics
13 relations
CYS2-HIS2 Zinc Fingers
Cell Nucleus
DNA-Binding Proteins
GLI2 gene
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Broader (2)
Kruppel-Like Transcription Factors
Nuclear Proteins
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
The sonic hedgehog-induced type 3 deiodinase facilitates tumorigenesis of basal cell carcinoma by reducing Gli2 inactivation.
C. Luongo
,
R. Ambrosio
,
S. Salzano
,
A. Dlugosz
,
C. Missero
,
M. Dentice
Endocrinology
2014
Corpus ID: 28475696
Thyroid hormone (TH) is an important regulator of growth, development, and metabolism. Most of the active TH T3 is generated by…
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2011
2011
Increased proteolytic processing of full‐length Gli2 transcription factor reduces the hedgehog pathway activity in vivo
Juan Li
,
Chengbing Wang
,
Yong Pan
,
Zengliang Bai
,
Baolin Wang
Developmental Dynamics
2011
Corpus ID: 31816602
The proteolytic processing of Gli2 and Gli3 full‐length transcription factors into repressors is a key step of the regulation in…
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2010
2010
Gli2 expression and human bladder transitional carcinoma cell invasiveness.
C. Mechlin
,
M. Tanner
,
Mengqian Chen
,
R. Buttyan
,
R. Levin
,
B. Mian
Journal of Urology
2010
Corpus ID: 24262497
2010
2010
Gli2 activator function in preosteoblasts is sufficient to mediate ihh‐dependent osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification
D. Kesper
,
Lydia Didt-Koziel
,
A. Vortkamp
Developmental Dynamics
2010
Corpus ID: 8693426
Signaling of Indian hedgehog (Ihh), one of the key regulators of endochondral ossification is mediated by transcription factors…
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2010
2010
Gli2 influences proliferation in the developing lung through regulation of cyclin expression.
Martin Rutter
,
Jinxia Wang
,
Zhenhao Huang
,
M. Kuliszewski
,
M. Post
American Journal of Respiratory Cell and…
2010
Corpus ID: 207750225
The sonic hedgehog (Shh) signaling pathway is crucial for normal lung development. In the lung, epithelial-produced Shh signals…
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2010
2010
Varying phenotypes in swine versus murine transgenic models constitutively expressing the same human Sonic hedgehog transcriptional activator, K5-HGLI2ΔN
Amy McCalla-Martin
,
Xiaoxin Chen
,
K. Linder
,
J. Estrada
,
J. Piedrahita
Transgenic research
2010
Corpus ID: 19915274
This study was undertaken to characterize the effects of constitutive expression of the hedgehog transcriptional activator, Gli2…
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Highly Cited
2008
Highly Cited
2008
Inhibition of Microtubule Assembly in Osteoblasts Stimulates Bone Morphogenetic Protein 2 Expression and Bone Formation through Transcription Factor Gli2
Ming Zhao
,
S. Ko
,
+6 authors
G. Mundy
Molecular and Cellular Biology
2008
Corpus ID: 6683704
ABSTRACT Bone morphogenetic protein 2 (BMP-2) is essential for postnatal bone formation and fracture repair. By screening…
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2003
2003
Expression of the GLI2 oncogene and its isoforms in human basal cell carcinoma
M. Tojo
,
H. Kiyosawa
,
K. Iwatsuki
,
K. Nakamura
,
F. Kaneko
British Journal of Dermatology
2003
Corpus ID: 23655947
Summary Background Mutations of the patched (Ptc) gene, a developmental regulator implicated in the signalling pathway via sonic…
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Review
2000
Review
2000
Neural patterning: the role of Nkx genes in the ventral spinal cord.
A. McMahon
Genes & Development
2000
Corpus ID: 14216601
The mammalian nervous system is extremely complex, consisting of many thousands of distinct neuronal cell types, any one of which…
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Review
2000
Review
2000
Achieving neuronal patterning by repression
D. Stone
,
A. Rosenthal
Nature Neuroscience
2000
Corpus ID: 35158193
The diffusible signal Sonic Hedgehog (Shh) controls cell type specification in the ventral spinal cord. Litingtung and Chiang now…
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