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Endothelin-2

Known as: EDN2, Endothelin 2, Endothelin-2 [Chemical/Ingredient] 
Endothelin-2, encoded by the human EDN2 gene, is a macrophage chemoattractant. Endothelins are endothelium-derived vasoconstrictor peptides. The… 
National Institutes of Health

Related topics

Related topics

21 relations
EDN2 geneEDN2 wt AlleleEndothelin-1Endothelin-3

Broader (1)

Endothelin

Narrower (1)

big endothelin 2

Papers overview

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Highly Cited
2002
Highly Cited
2002
Endothelin-2 is a hypoxia-induced autocrine survival factor for breast tumor cells.
Endothelins (ETs) are a group of vasoactive peptides (ET-1, ET-2 and ET-3) produced by many cell types that bind to G-protein… 
1996
1996
Therapeutic Potential of Endothelin Receptor Antagonists in Cerebrovascular Disease
SummaryThe actions of the endothelins (endothelin-I. endothelin-2 and endothelin-3) are mediated via endothelin-A (EA) and… 
1995
1995
Regulation of cyclic AMP production in adult human ciliary processes.
Highly Cited
1995
Highly Cited
1995
Cloning and sequencing of a human endothelin converting enzyme in renal adenocarcinoma (ACHN) cells producing endothelin-2.
Endothelin (ET)-2 is a 21 residue vasoactive peptide which is biosynthesized from big ET-2(1-38) by a specific cleavage at Trp21… 
1993
1993
Characterization of endothelin isoforms in human heart: endothelin-2 demonstrated.
In humans, three endothelin (ET) isoforms are predicted to exist by analysis of genomic DNA. However, evidence for the presence… 
1993
1993
Identification of endothelin-1, endothelin-2 and endothelin-3 in human endometrium.
This study determined the presence of specific endothelin isoforms in human endometrium using high performance liquid… 
Review
1992
Review
1992
Vasoactive mediators released by endothelins.
Highly Cited
1991
Highly Cited
1991
Human placenta expresses endothelin gene and corresponding protein is excreted in urine in increasing amounts during normal pregnancy.
1991
1991
Immunoreactive endothelin in human plasma, urine, milk, and saliva.
Using a highly sensitive radioimmunoassay, elevated plasma immunoreactive endothelin (ir-ET) levels were found in patients with… 
Highly Cited
1991
Highly Cited
1991
Endothelin activation of an inwardly rectifying K+ current in atrial cells.
Various tissues including heart express specific binding sites for endothelin. Endothelins have been reported to increase the… 
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