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Endothelin-2

Known as: EDN2, Endothelin 2, Endothelin-2 [Chemical/Ingredient] 
Endothelin-2, encoded by the human EDN2 gene, is a macrophage chemoattractant. Endothelins are endothelium-derived vasoconstrictor peptides. The… 
National Institutes of Health

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Related topics

21 relations
EDN2 geneEDN2 wt AlleleEndothelin-1Endothelin-3

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Endothelin

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big endothelin 2

Papers overview

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Highly Cited
2002
Highly Cited
2002
Endothelin-2 is a hypoxia-induced autocrine survival factor for breast tumor cells.
Endothelins (ETs) are a group of vasoactive peptides (ET-1, ET-2 and ET-3) produced by many cell types that bind to G-protein… 
Highly Cited
1998
Highly Cited
1998
Rapid activation of the novel serine/threonine protein kinase, protein kinase D by phorbol esters, angiotensin II and PDGF‐BB in vascular smooth muscle cells
1993
1993
Characterization of endothelin isoforms in human heart: endothelin-2 demonstrated.
In humans, three endothelin (ET) isoforms are predicted to exist by analysis of genomic DNA. However, evidence for the presence… 
Highly Cited
1992
Highly Cited
1992
Presence of messenger ribonucleic acid for endothelin-1, endothelin-2, and endothelin-3 in human endometrium and a change in the ratio of ETA and ETB receptor subtype across the menstrual cycle.
The aim of the present study was to determine whether mRNA for the three endothelin peptides (endothelin-1, endothelin-2, and… 
Highly Cited
1991
Highly Cited
1991
Localization and characterization of endothelin receptor binding sites in the rat brain visualized by in vitro autoradiography4
Highly Cited
1991
Highly Cited
1991
Human placenta expresses endothelin gene and corresponding protein is excreted in urine in increasing amounts during normal pregnancy.
Highly Cited
1990
Highly Cited
1990
Endothelin mobilizes Ca2+ from a caffeine- and ryanodine-insensitive intracellular pool in rat atrial cells.
Highly Cited
1990
Highly Cited
1990
Astrocytes Are Target Cells for Endothelins and Sarafotoxin
Abstract: Endothelin‐I, endothelin‐3, and the snake venom toxin sarafotoxin 56b stimulate the hydrolysis of phosphatidylinositol… 
1990
1990
Endothelin-3 concentrations in human plasma: the increased concentrations in patients undergoing haemodialysis.
Highly Cited
1989
Highly Cited
1989
cDNA cloning and chromosomal assignment of the gene encoding endothelin 3.
The vasoactive peptide endothelin 1 (ET1) is encoded by a well characterized gene located on human chromosome 6. Recently, two… 
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