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Drug Kinetics
Known as:
PK
, Pharmacokinetics
, Kinetics, Drug
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Dynamic and kinetic mechanisms of exogenous chemical and DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION…
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National Institutes of Health
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Related topics
Related topics
20 relations
Biological Availability
Body part
Body space
Body tissue
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Narrower (6)
Drug effect disorder
Metabolic Clearance Rate
drug absorption
drug binding
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Broader (3)
Pharmacology
Uptake
pharmacology and toxicology
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
Stimulus-dependent modulation of [(3)H]norepinephrine release from rat neocortical slices by gabapentin and pregabalin.
D. Dooley
,
Cindy M. Donovan
,
T. Pugsley
Journal of Pharmacology and Experimental…
2000
Corpus ID: 6156407
Gabapentin (GBP; Neurontin) has proven efficacy in several neurological and psychiatric disorders yet its mechanism of action…
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Review
1998
Review
1998
Podophyllotoxins: current status and recent developments.
Y. Damayanthi
,
J. Lown
Current Medicinal Chemistry
1998
Corpus ID: 3049207
Podophyllotoxin is a natural product isolated from Podophyllum peltatum and Podophyllum emodi and has long been known to possess…
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Highly Cited
1990
Highly Cited
1990
Mechanism of cardiac defibrillation in open-chest dogs with unipolar DC-coupled simultaneous activation and shock potential recordings.
F. Witkowski
,
P. Penkoske
,
Robert Plonsey
Circulation
1990
Corpus ID: 14632111
The automatic implantable cardioverter-defibrillator has been shown to dramatically improve survival. The future refinement of…
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Highly Cited
1988
Highly Cited
1988
Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. II. Evidence for N-methyl-D-aspartate receptor antagonist properties.
C. Carter
,
J. Benavides
,
+7 authors
E. Mackenzie
Journal of Pharmacology and Experimental…
1988
Corpus ID: 33610654
The effects of the anti-ischemic agents ifenprodil and its derivative SL 82.0715 ((+/-)-alpha-(4-chlorophenyl)-4-[(4-fluorophenyl…
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Highly Cited
1983
Highly Cited
1983
Regulation of immunity in rats by lactogenic and growth hormones.
É. Nagy
,
I. Bérczi
,
H. Friesen
Acta Endocrinologica
1983
Corpus ID: 22159831
Antibody formation to sheep red blood cells and the development of contact dermatitis in response to dinitrochlorobenzene are…
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Highly Cited
1982
Highly Cited
1982
Characterization of the peripheral and central effects of SK&F 82526, a novel dopamine receptor agonist.
R. A. Hahn
,
J. R. Wardell
,
H. Sarau
,
P. Ridley
Journal of Pharmacology and Experimental…
1982
Corpus ID: 26285368
SK&F 82526 (6-chloro-7,8-dihydroxy-1-(p-hydroxyphenyl)-2,3,4,5-tetrahydro-(1H)-3-benzazepine) was evaluated for its peripheral…
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Review
1982
Review
1982
Angiotensin‐converting enzyme inhibitors: Medicinal chemistry and biological actions
E. Petrillo
,
M. Ondetti
Medicinal research reviews (Print)
1982
Corpus ID: 22612542
A decade of experimentation, with work in the last four years greatly accelerated by the availability of captopril, favors the…
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Highly Cited
1980
Highly Cited
1980
Calcium antagonistic drugs. Mechanism of action.
J. Church
,
T. Zsotér
Canadian Journal of Physiology and Pharmacology
1980
Corpus ID: 21558828
Calcium antagonists represent a new class of drugs, which were suggested to act by a selective inhibition of Ca2+ influx through…
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Review
1972
Review
1972
Studies on the mechanism of action of local anesthetics with phospholipid model membranes.
D. Papahadjopoulos
Biochimica et Biophysica Acta
1972
Corpus ID: 37398733
Highly Cited
1969
Highly Cited
1969
The Effect of Prostaglandin F2α on the Progestogen Content of Ovaries from Pseudopregnant Rats
B. Pharriss
,
L. Wyngarden
Proceedings of the Society for Experimental…
1969
Corpus ID: 37217005
Summary Prostaglandin F2α was infused into pseudopregnant rats for 2 days (days 5 and 6) at 1 mg/kg/day. The infusion tubing was…
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