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Degenerin Sodium Channels

Known as: Degenerins, Degenerin Sodium Channels [Chemical/Ingredient], Degenerin Ion Channels 
A family of mechanosensitive sodium channels found primarily in NEMATODES where they play a role in CELLULAR MECHANOTRANSDUCTION. Degenerin sodium… 
National Institutes of Health

Related topics

Related topics

8 relations
ASIC2 geneASIC2 protein, humanIn BloodProcess of secretion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
The amiloride-sensitive endothelial sodium channel and vascular tone.
See related article, pp 1053–1059 In this issue of Hypertension , Jeggle et al1 provide important new insights into the… 
2009
2009
Insights into the molecular determinants of proton inhibition in an acid-inactivated degenerins and mammalian epithelial Na(+) channel.
Mammalian ASIC channels of the DEG/ENaC superfamily are gated by extracellular protons and function to mediate touch and pain… 
Review
2007
Review
2007
Mechanotransduction in Caenorhabditis elegans
One of the looming mysteries in signal transduction today is the question of how mechanical signals, such as pressure or… 
Highly Cited
1998
Highly Cited
1998
A new member of the amiloride-sensitive sodium channel family in Drosophila melanogaster peripheral nervous system.
Amiloride sensitivity is a common characteristic of structurally related cationic channels that are associated with a wide range… 
Review
1998
Review
1998
Osmotic pressure regulates abg-rENaC expressed in Xenopus oocytes ’ ’
IN THE CURRENT article in focus, Ji et al. (Ref. 5, see p. C1182 in this issue) present evidence that osmotic pressure can… 
1997
1997
BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels
The recently defined DEGyENaC superfam- ily of sodium channels includes subunits of the amiloride- sensitive epithelial sodium… 
Review
1997
Review
1997
The amiloride-sensitive Na+ channel: from primary structure to function.
1997
1997
A molecular model for mechanosensation in Caenorhabditis elegans.
Sensory signaling by chemicals and light are fairly well understood in molecular terms, but the molecules needed for mechanical… 
1996
1996
The human degenerin MDEG, an amiloride-sensitive neuronal cation channel, is localized on chromosome 17q11.2-17q12 close to the microsatellite D17S798.
Review
1996
Review
1996
Molecular biology of the amiloride‐sensitive epithelial Na+ channel
The amiloride‐sensitive epithelial Na+ channel is formed by the assembly of three homologous subunits, alpha, beta and gamma. The… 
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