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CVT 124
Known as:
CVT-124
National Institutes of Health
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Papers overview
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2002
2002
Preparation of 8-substituted xanthine CVT-124 precursor by late stage pyrimidine ring closure.
R. Herr
,
P. F. Vogt
,
H. Meckler
,
M. Trova
,
S. Schow
,
R. Petter
Journal of Organic Chemistry
2002
Corpus ID: 42824292
To develop a novel route for the scaleable synthesis of the chiral xanthine CVT-124 (1, aka. BG9719), a method for the late stage…
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2000
2000
BG9719 (CVT-124) a highly potent adenosine A-1 receptor antagonist. Initial experience in cirrhotic patients with diuretic refractory ascites
J. O’Beirne
,
C. Bouvier
,
+4 authors
M. Hamilton
2000
Corpus ID: 71874101
1998
1998
CVT-124, a novel adenosine A1 receptor antagonist with unique diuretic activity.
Miklos Gellai
,
George F. Schreiner
,
R. Ruffolo
,
Tracey Fletcher
,
Robin DeWolf
,
David P. Brooks
Journal of Pharmacology and Experimental…
1998
Corpus ID: 6332847
Administration of the selective adenosine A1 receptor antagonist, CVT-124, to conscious chronically instrumented rats resulted in…
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1998
1998
Renal effects of BG9719, a specific A1 adenosine receptor antagonist, in congestive heart failure
A. Wolff
,
S. Skettino
,
E. Beckman
,
L. Belardinelli
1998
Corpus ID: 71289607
A1 adenosine receptors mediate renal afferent arteriolar vasoconstriction when distal tubular Na+ concentrations increase…
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Highly Cited
1997
Highly Cited
1997
Synthesis and biological evaluation of the enantiomers of the potent and selective A1-adenosine antagonist 1,3-dipropyl-8-[2-(5,6-epoxynorbonyl)]-xanthine.
J. R. Pfister
,
L. Belardinelli
,
+6 authors
G. Schreiner
Journal of Medicinal Chemistry
1997
Corpus ID: 24173477
The individual enantiomers 8 and 12 of the potent and highly selective racemic A1-adenosine antagonist 1,3-dipropyl-8-[2-(5,6…
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