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Anti-gpA33/CD3 Monoclonal Antibody MGD007
Known as:
Humanized gpA33 x CD3 DART (TM) Protein MGD007
, MGD007
An anti-glycoprotein A33 (gpA33)/anti-CD3 bispecific humanized monoclonal antibody with potential immunostimulatory and antineoplastic activities…
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National Institutes of Health
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1 relation
antigen binding
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
A Phase I, first-in-human, open label, dose escalation study of MGD007, a humanized gpA33 × CD3 dual-affinity re-targeting (DART®) protein in patients with relapsed/refractory metastatic colorectal…
H. Hurwitz
,
T. Crocenzi
,
+4 authors
J. Wigginton
Journal of Immunotherapy for Cancer
2014
Corpus ID: 18019127
Colorectal carcinoma (CRC) is the third-most commonly diagnosed cancer in the U.S., and the third-most common cause of cancer…
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2014
2014
Abstract 669: Development of MGD007, a gpA33 x CD3 bi-specific DART for T-cell immunotherapy of metastatic colorectal cancer
P. Moore
,
R. Alderson
,
+6 authors
S. Johnson
2014
Corpus ID: 56488509
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Introduction: Encouraging clinical responses have been…
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