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Animals, Transgenic
Known as:
Transgenic
, Animal, Transgenic
, Transgenic Animal
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Animals, or the offspring of such animals, into which cloned genetic material has been experimentally transferred by microinjection of foreign DNA…
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National Institutes of Health
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Related topics
Related topics
9 relations
Broader (2)
Animals
Animals, Genetically Modified
Chimera organism
Gene Targeting
Genetic Engineering
Mice, Knockout
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors.
R. Chiarle
,
J. Gong
,
+8 authors
G. Inghirami
Blood
2003
Corpus ID: 22788913
Anaplastic Large Cell Lymphomas (ALCLs) carry translocations in which the anaplastic lymphoma kinase (ALK) gene is juxtaposed to…
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Highly Cited
2002
Highly Cited
2002
Pronounced Eosinophilic Lung Inflammation and Th2 Cytokine Release in Human Lipocalin-Type Prostaglandin D Synthase Transgenic Mice1
Y. Fujitani
,
Y. Kanaoka
,
K. Aritake
,
N. Uodome
,
Kazue Okazaki-Hatake
,
Y. Urade
Journal of Immunology
2002
Corpus ID: 25272953
PGD2 is a major lipid mediator released from mast cells, but little is known about its role in the development of allergic…
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Highly Cited
2002
Highly Cited
2002
Alterations in behavior, amyloid p‐42, caspase‐3, and Cox‐2 in mutant PS2 transgenic mouse model of Alzheimer's disease
Dae-Yeop Hwang
,
K. Chae
,
+13 authors
Y. K. Kim
The FASEB Journal
2002
Corpus ID: 26126286
Alzheimer's disease (AD) occurs when neurons in the memory and cognition regions of the brain are accompanied by an accumulation…
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Highly Cited
2000
Highly Cited
2000
Germinal Center Initiation, Variable Gene Region Hypermutation, and Mutant B Cell Selection without Detectable Immune Complexes on Follicular Dendritic Cells
L. Hannum
,
A. Haberman
,
Shannon M. Anderson
,
M. Shlomchik
Journal of Experimental Medicine
2000
Corpus ID: 3914672
Serum antibody (Ab) can play several roles during B cell immune responses. Among these is to promote the deposition of immune…
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Highly Cited
1998
Highly Cited
1998
Enhanced myocardial contractility and increased Ca2+ transport function in transgenic hearts expressing the fast-twitch skeletal muscle sarcoplasmic reticulum Ca2+-ATPase.
E. Loukianov
,
Yong Ji
,
+7 authors
Muthu Periasamy
Circulation Research
1998
Corpus ID: 18687273
In this study, we investigated whether the fast-twitch skeletal muscle sarco(endo)plasmic reticulum Ca2+ transport pump (SERCA1a…
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Highly Cited
1997
Highly Cited
1997
Constitutive Expression of Interleukin (IL)-4 In Vivo Causes Autoimmune-type Disorders in Mice
K. Erb
,
B. Rüger
,
Maja von Brevern
,
B. Ryffel
,
A. Schimpl
,
Karen Rivett
Journal of Experimental Medicine
1997
Corpus ID: 7664606
The transgenic (tg) expression of interleukin (IL)-4 under the control of a major histocompatibility complex (MHC) class I…
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Highly Cited
1996
Highly Cited
1996
Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self- reactive T cells
T. Zhou
,
Jianhua Cheng
,
+5 authors
J. Mountz
Journal of Experimental Medicine
1996
Corpus ID: 10454739
The Nur77/Nurr1 family of DNA binding proteins has been reported to be required for the signal transduction of CD3/T cell…
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Highly Cited
1996
Highly Cited
1996
Oral tolerance in myelin basic protein T-cell receptor transgenic mice: suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cells.
Youhai H. Chen
,
J. Inobe
,
V. Kuchroo
,
Jody L. BARONt
,
C. Janeway
,
H. Weiner
Proceedings of the National Academy of Sciences…
1996
Corpus ID: 25582176
Orally administered antigens induce a state of immunologic hyporesponsiveness termed oral tolerance. Different mechanisms are…
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Highly Cited
1994
Highly Cited
1994
Ectopic Hoxa-1 induces rhombomere transformation in mouse hindbrain.
M. Zhang
,
H. Kim
,
+7 authors
J. Grippo
Development
1994
Corpus ID: 35436200
Homeobox genes are expressed with a specific spatial and temporal order, which is essential for pattern formation during the…
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Highly Cited
1994
Highly Cited
1994
The use of shuttle vectors for mutation analysis in transgenic mice and rats.
M. Dycaico
,
G. Provost
,
P. L. Kretz
,
Sherrie L. Ransom
,
Jane C. Moores
,
Jay M. Short
Mutation research
1994
Corpus ID: 28925924
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