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Acetylcholinesterase Inhibitors
Known as:
Acetylcholinesterase Inhibitor
, Acetylcholine Hydrolase Inhibitor
, AcCholE Inhibitor
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Any substance that inhibits acetylcholinesterase (AchE), an enzyme that breaks down acetylcholine (Ach) in the synaptic cleft. Inhibition of…
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National Institutes of Health
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Related topics
Related topics
2 relations
Cholinesterase Inhibitor [EPC]
Broader (1)
Cholinesterase Inhibitors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors.
F. Leonetti
,
M. Catto
,
+4 authors
A. Carotti
Bioorganic & Medicinal Chemistry
2008
Corpus ID: 29259465
Highly Cited
2005
Highly Cited
2005
Novel Dimeric Acetylcholinesterase Inhibitor Bis(7)-tacrine, but Not Donepezil, Prevents Glutamate-induced Neuronal Apoptosis by Blocking N-Methyl-d-aspartate Receptors*
Wenming Li
,
R. Pi
,
+15 authors
Yifan Han
Journal of Biological Chemistry
2005
Corpus ID: 7778868
The neuroprotective properties of bis(7)-tacrine, a novel dimeric acetylcholinesterase (AChE) inhibitor, on glutamate-induced…
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Highly Cited
2005
Highly Cited
2005
Stimulation of nicotinic acetylcholine receptors protects motor neurons.
T. Nakamizo
,
J. Kawamata
,
+5 authors
S. Shimohama
Biochemical and Biophysical Research…
2005
Corpus ID: 37749673
Highly Cited
2004
Highly Cited
2004
M2 muscarinic receptors in pontine reticular formation of C57BL/6J mouse contribute to rapid eye movement sleep generation
C. Coleman
,
R. Lydic
,
H. Baghdoyan
Neuroscience
2004
Corpus ID: 22232345
2004
2004
Prediction of psychiatric response to donepezil in patients with mild to moderate Alzheimer's disease
Makoto Tanaka
,
C. Namiki
,
+5 authors
T. Kita
Journal of Neurological Sciences
2004
Corpus ID: 20792308
Review
2001
Review
2001
Muscarinic agonists and antagonists in the treatment of Alzheimer's disease.
W. Greenlee
,
J. Clader
,
+21 authors
K. Cox
Il Farmaco
2001
Corpus ID: 34206300
Highly Cited
1992
Highly Cited
1992
Tacrine-induced seizures and brain damage in LiCl-treated rats can be prevented by N omega-nitro-L-arginine methyl ester.
G. Bagetta
,
M. Iannone
,
A. Scorsa
,
G. Nisticó
European Journal of Pharmacology
1992
Corpus ID: 36763316
Highly Cited
1985
Highly Cited
1985
Acetylcholinesterase from fetal bovine serum. Purification and characterization of soluble G4 enzyme.
J. Ralston
,
R. S. Rush
,
B. P. Doctor
,
A. D. Wolfe
Journal of Biological Chemistry
1985
Corpus ID: 23422039
Highly Cited
1979
Highly Cited
1979
Effects of physostigmine and lecithin on memory in Alzheimer disease
B. Peters
,
Harvey S. Levin
Annals of Neurology
1979
Corpus ID: 43142847
Because there is evidence that central cholinergic mechanisms are depleted in dementia, we studied the effects of central…
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Highly Cited
1972
Highly Cited
1972
Purification by affinity chromatography of acetylcholinesterase from electric organ tissue of the electric eel subsequent to tryptic treatment.
Y. Dudai
,
I. Silman
,
N. Kalderon
,
S. Blumberg
Biochimica et Biophysica Acta
1972
Corpus ID: 31963720
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