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6-methoxy-2-naphthylacetic acid

Known as: 6-MNA cpd, 6MNA 
National Institutes of Health

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2 relations

Broader (2)

Enzyme InhibitorsNaphthaleneacetic Acids

Papers overview

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2015
2015
Enhanced skin permeation of 6-methoxy-2-naphthylacetic acid by salt formation
Abstract The aim of this work was to prepare salts of 6-methoxy-2-naphthylacetic acid (6-MNA) to improve its physicochemical… 
2014
2014
A novel injection strategy of flurbiprofen axetil by inhibiting protein binding with 6-methoxy-2-naphthylacetic acid
Flurbiprofen axetil (FPA) is an injection product and a prodrug of a non-steroidal anti-inflammatory drug (NSAID). After… 
2011
2011
[Determination of nabumetone and 6-methoxy-2-naphthylacetic acid in plasma using HPLC with UV and MS detection].
The study aimed to establish and validate an analytical method for the determination of nabumetone and 6-methoxy-2-naphthylacetic… 
2008
2008
Simultaneous determination of two anti-inflammatory drugs in serum using isopotential fluorimetry.
2006
2006
Evaluation of hydroxyimine as cytochrome P450-selective prodrug structure.
Hydroxyimine derivatives of ketoprofen (1) and nabumetone (2) were synthesized and evaluated in vitro and in vivo as cytochrome… 
2004
2004
Regulation of metalloproteinases and NF‐κB activation in rabbit synovial fibroblasts via E prostaglandins and Erk: contrasting effects of nabumetone and 6MNA
Nabumetone is a prodrug that is converted in vivo into 6‐methoxy‐2‐naphthylacetic acid (6MNA), a cyclooxygenase inhibitor with… 
2000
2000
Extractionless determination of 6-methoxy-2-naphthylacetic acid, a major metabolite of nabumetone, in human plasma by high-performance liquid chromatography.
1999
1999
Efficacy of the selective prostaglandin synthase type 2 inhibitor nimesulide in blocking basal prostaglandin production and delaying glucocorticoid-induced premature labor in sheep.
1999
1999
[Determination of 6-methoxy-2-naphthylacetic acid, a major metabolite of nabumetone, in human plasma by HPLC].
This paper reports a sensitive and rapid method for determining 6-methoxy-2-naphthylacetic acid (MNA), a major metabolite of… 
1996
1996
Disposition and excretion of 6-methoxy-2-naphthylacetic acid, the active metabolite of nabumetone in horses.
OBJECTIVE To examine, in horses, the disposition and excretion of the active metabolite 6-methoxy-2-naphthylacetic acid (6MNA) of… 
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