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5,8,11,14-Eicosatetraynoic Acid
Known as:
5,8,11,14 Eicosatetraynoic Acid
, 5,8,11,14-Eicosatetraynoic Acid [Chemical/Ingredient]
, ETYA
A 20-carbon unsaturated fatty acid containing 4 alkyne bonds. It inhibits the enzymatic conversion of arachidonic acid to prostaglandins E(2) and F…
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National Institutes of Health
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11 relations
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4,7,10,13-eicosatetraynoic acid
5,8,11,14-heneicosatetraynoic acid
Triarachidonin
In Blood
Process of secretion
agonists
analogs & derivatives
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1992
Highly Cited
1992
Contribution of NO and cytochrome P450 to the vasodilator effect of bradykinin in the rat kidney
D. Fulton
,
J. Mcgiff
,
J. Quilley
British Journal of Pharmacology
1992
Corpus ID: 23873150
1 Inhibition of nitric oxide generation with Nw‐nitro‐l‐arginine (nitroarginine) reduced vasodilator responses to bradykinin and…
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Highly Cited
1987
Highly Cited
1987
Mechanism of histamine actions in human coronary arteries.
N. Toda
Circulation Research
1987
Corpus ID: 15107964
Helical strips of human coronary arteries contracted in response to histamine concentration dependently, they relaxed with low…
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Highly Cited
1985
Highly Cited
1985
Inhibition of neutrophil phospholipase A2 by p-bromophenylacyl bromide, nordihydroguaiaretic acid, 5,8,11,14-eicosatetraynoic acid and quercetin.
C. Lanni
,
E. Becker
International Archives of Allergy and Applied…
1985
Corpus ID: 45574109
The lipoxygenase and/or cyclooxygenase inhibitors nordihydroguaiaretic acid (NDGA), 4,8,11,14-eicosatetraynoic acid (ETYA) and…
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Highly Cited
1984
Highly Cited
1984
Comparative effects of indomethacin, acetylenic acids, 15-HETE, nordihydroguaiaretic acid and BW755C on the metabolism of arachidonic acid in human leukocytes and platelets.
Hassan Salari
,
Pierre Braquet
,
P. Borgeat
Prostaglandins Leukotrienes and Medicine
1984
Corpus ID: 34277864
Highly Cited
1983
Highly Cited
1983
Role of the endothelium in the vasodilator response of rat thoracic aorta to histamine.
J. van de Voorde
,
I. Leusen
European Journal of Pharmacology
1983
Corpus ID: 4533076
Highly Cited
1981
Highly Cited
1981
Evidence for inhibition of leukotriene A4 synthesis by 5,8,11,14-eicosatetraynoic acid in guinea pig polymorphonuclear leukocytes.
G. Bokoch
,
P. Reed
Journal of Biological Chemistry
1981
Corpus ID: 25234359
The sensitivity of the 5-lipoxygenase to inhibition by 5,8,11,14-eicosatetraynoic acid (ETYA) is species- and/or tissue-dependent…
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Highly Cited
1981
Highly Cited
1981
Arachidonic acid 15-lipoxygenase from rabbit peritoneal polymorphonuclear leukocytes. Partial purification and properties.
S. Narumiya
,
J. Salmon
,
F. Cottee
,
B. Weatherley
,
R. Flower
Journal of Biological Chemistry
1981
Corpus ID: 29607586
Highly Cited
1981
Highly Cited
1981
Effect of various lipoxygenase metabolites of arachidonic acid on degranulation of polymorphonuclear leukocytes.
G. Bokoch
,
P. Reed
Journal of Biological Chemistry
1981
Corpus ID: 6893159
Highly Cited
1979
Highly Cited
1979
Isolation of a new lipoxygenase metabolite of arachidonic acid, 8. 11, 12-trihydroxy-5,9,14-eicosatrienoic acid from human platelets.
R. Bryant
,
J. Bailey
Prostaglandins
1979
Corpus ID: 30215226
Highly Cited
1970
Highly Cited
1970
Enzyme inhibition by acetylenic compounds.
D. Downing
,
D. Ahern
,
Madeline Bachta
Biochemical and Biophysical Research…
1970
Corpus ID: 7318765
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