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3,6-bis(2-piperidinoethoxy)acridine trihydrochloride
Known as:
3,6-bis-(2-piperidinoethoxyl)acridine trihydrochloride
, Acridine, 3,6-bis(2-(1-piperidinyl)ethoxy) trihydrochloride
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Acridines
Narrower (1)
CL 246738
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
NSC 23766 , a Widely Used Inhibitor of Rac 1 Activation , Additionally Acts as a Competitive Antagonist at Muscarinic Acetylcholine Receptors s
Magdolna K. Levay
,
K. Krobert
,
+6 authors
T. Wieland
2013
Corpus ID: 5348617
Small molecules interfering with Rac1 activation are considered as potential drugs and are already studied in animal models. A…
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2007
2007
Pharmacological Properties of 3-Amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878), a Novel Therapeutic Agent for Diarrhea-Predominant Irritable…
S. Tamaoki
,
Yukinao Yamauchi
,
Youichi Nakano
,
Sayuri Sakano
,
A. Asagarasu
,
Michitaka Sato
Journal of Pharmacology and Experimental…
2007
Corpus ID: 6015413
3-Amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878) is a novel compound with…
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2007
2007
Serotonin receptor involvement in effects of restraint on female rat lordosis behavior
L. Uphouse
,
C. Hiegel
,
E. Perez
,
J. Guptarak
Pharmacology, Biochemistry and Behavior
2007
Corpus ID: 35353757
1991
1991
The mechanism of action of a synthetic immunomodulator, 3,6-bis(2-piperidinoethoxy)acridine trihydrochloride (CL 246,738), in natural killer cell activation in animals.
V. Ruszala-Mallon
,
J. Silva
,
A. Lumanglas
,
F. Durr
,
B. S. Wang
International Journal of Immunopharmacology
1991
Corpus ID: 4445846
1990
1990
Biological and clinical effects of the oral immunomodulator 3,6-bis(2-piperidinoethoxy)acridine trihydrochloride in patients with malignancy.
Litton Gj
,
R. Hong
,
Grossberg Se
,
D. Vechlekar
,
Goodavish Cn
,
E. Borden
Journal of Biological Response Modifiers
1990
Corpus ID: 9467914
CL 246,738 is a synthetic heterocyclic of the acridine class that has immunomodulating, interferon (IFN)-inducing, and antitumor…
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1989
1989
The in vivo antiviral effect of CL246,738 is mediated by the independent induction of interferon-alpha and interferon-beta.
M. Sarzotti
,
D. Coppenhaver
,
I. Singh
,
J. Poast
,
S. Baron
Journal of Interferon Research
1989
Corpus ID: 39084079
An interferon (IFN) inducer and immunomodulator, CL246,738 [3,6-bis(2-piperidinoethoxy)acridine trihydrochloride], protected mice…
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1986
1986
The mechanism of action of 3,6-bis(2-piperidinoethoxy)acridine trihydrochloride (CL 246,738) in the potentiation of natural killer cells.
B. S. Wang
,
A. Lumanglas
,
J. Silva
,
V. Ruszala-Mallon
,
F. Durr
Journal of Immunology
1986
Corpus ID: 8052743
An effort has been made to determine the mechanism by which the immunomodulator 3,6-bis(2-piperidinoethoxy)acridine…
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1985
1985
Induction of tumor-inhibitory macrophages with a novel synthetic immunomodulator, 3,6-bis(2-piperidinoethoxy)acridine trihydrochloride (CL 246,738).
B. S. Wang
,
A. Lumanglas
,
V. Ruszala-Mallon
,
F. Durr
Journal of Immunology
1985
Corpus ID: 27620907
3,6-bis(2-piperidinoethoxy)acridine trihydrochloride (CL 246,738) has been investigated for its immunomodulatory effect on murine…
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